Reprinted with permission from N. Kaur et al. Role of lattice disorder in water-mediated dissociation of pharmaceutical cocrystal systems. Mol Pharm, (16)7, 3167-3177 (2019).
2023
- R. Lalge, N.S. Krishna Kumar, R. Suryanarayanan. Understanding the Effect of Nucleation in Amorphous Solid Dispersions through Time-Temperature Transformation. Mol Pharm, 20(8), 4196-4209 (2023).
- B. Munjal, K. DeBoyace, F. Cao, J.F. Krzyzaniak, K.K. Arora, R. Suryanarayanan. Drug Phase Transformation and Water Redistribution during Continuous Tablet Manufacturing: A Case Study of Carbamazepine Dihydrate. Mol Pharm, 20(7), 3427-3437 (2023).
2022
- N.S. Krishna Kumar, R. Suryanarayanan. Crystallization Propensity of Amorphous Pharmaceuticals: Kinetics and Thermodynamics. Mol Pharm, 19(2), 472-483 (2022).
2021
- R. Chinnasamy, B. Munjal, R. Suryanarayanan, A.M.P. Peedikakkal, M.K. Mishra, S. Ghosh. Pressure and Temperature Induced Dual Responsive Molecular Crystals: Effect of Polymorphism. Cryst Growth Des, 22(1), 615-624 (2021).
- N. Kaur, G. Haustad, R. Suryanarayanan. Use of Atomic Force Microscopy (AFM) to monitor surface crystallization in caffeine-oxalic acid (CAFOXA) cocrystal compacts. Int J Pharm, 609, 121196 (2021).
2020
- K.K. Amponsah-Efah, C. Glorieux, J. Thoen, R. Suryanarayanan. Effect of glycerol on the order of the mesophase transitions of super-cooled itraconazole. J Mol Liquids, 114222 (2020).
- N. Kaur, V.G. Young Jr., Y. Su, R. Suryanarayanan. Partial dehydration of levothyroxine sodium pentahydrate in a drug product environment: Structural insights into stability. Mol Pharm, 17(10), 3915-3929 (2020).
- S. Koranne, R. Lalge, R. Suryanarayanan. Modulation of Microenvironmental Acidity: A Strategy to Mitigate Salt Disproportionation in Drug Product Environment. Mol Pharm, 17(4), 1324-1334 (2020).
2019
- R. Tanaka, N.K. Duggirala, Y. Hattori, M. Otsuka, R. Suryanarayanan. Formation of Indomethacin-Saccharin Cocrystals during Wet Granulation: Role of Polymeric Excipients. Mol Pharm, 17(1):274-283 (2019).
- N. Kaur, N.K. Duggirala, R. Suryanarayanan. The role of lattice disorder in water mediated dissociation of pharmaceutical cocrystal systems. Mol Pharm, 16(7), 3167-3177 (2019).
- S. Koranne, J.F. Krzyzaniak, S. Luthra, K.K. Arora, R. Suryanarayanan. Role of conformer and excipient properties on the solid-state stability of theophylline cocrystals. Cryst Growth Des, 19(2), 868-875 (2019).
- N.K. Thakral, S. Thakral, G.A. Stephenson, R. Sedlock, R. Suryanarayanan. Compression-induced polymorphic transformation in tablets: Role of shear stress and development of mitigation strategies. J Pharm Sci, 108(1), 476-484 (2019).
2018
- S. Koranne, A. Sahoo, J.F. Krzyzaniak, S. Luthra, R. Suryanarayanan. Challenges in transitioning cocrystals from bench to bedside: Dissociation in prototype drug product environment. Mol Pharm, 15(8), 3297-3307 (2018).
- S. Thakral, N.K. Thakral, R. Suryanarayanan. Estimation of drug particle size in intact tablets by two dimensional X-ray diffractometry. J Pharm Sci, 107(1), 231-238 (2018).
2017
- S. Koranne, R. Govindarajan, R. Suryanarayanan. Investigation of spatial heterogeneity of salt disproportionation in tablets by synchrotron X-ray diffractometry. Mol Pharm, 14(4), 1133-1144 (2017).
2016
- N.K. Thakral, R.J. Behme, A. Aburub, J.A. Peterson, T.A. Woods, B.A. Diseroad, R. Suryanarayanan, G.A. Stephenson. Salt disproportionation in the solid state: Role of solubility and counterion volatility. Mol Pharm, 13(5), 4141-4151 (2016).
- P. Mistry, R. Suryanarayanan. Strength of drug-polymer interactions: Implications for crystallization in dispersions. Cryst Growth Des, 16(9), 5141-5149 (2016).
- M. Mehta, G.B. McKenna, R. Suryanarayanan. Molecular mobility in glassy dispersions. J Chem Phys, 144, 204506 (2016).
- M. Mehta, K. Kothari, V. Ragoonanan, R. Suryanarayanan. Effect of Water on Molecular Mobility and Physical Stability of Amorphous Pharmaceuticals. Mol Pharm, 13(4), 1339-1346 (2016).
- M. Mehta, V. Ragoonanan, G.B. McKenna, R. Suryanarayanan. Correlation between Molecular Mobility and Physical Stability in Pharmaceutical Glasses. Mol Pharm, 13(4), 1267-1277 (2016).
2015
- N.K. Thakral, H. Yamada, G.A. Stephenson, R. Suryanarayanan. Spatial distribution of trehalose dihydrate crystallization in tablets by X-ray diffractometry. Mol Pharm, 12(10), 3766-3775 (2015).
- N.K. Thakral, S. Mohapatra, G. Stephenson, R. Suryanarayanan. Compression-induced crystallization of amorphous indomethacin in tablets: characterization of spatial heterogeneity by two-dimensional X-ray diffractometry. Mol Pharm, 12(1), 253-263 (2015).
- K. Arora, S. Bhardwaj, P. Mistry, R. Suryanarayanan. Modulating the dehydration conditions of adefovir dipivoxil dihydrate to obtain different physical forms of anhydrate. J Pharm Sci, 104(3), 1056-1064 (2015).
2014
- S. Bhattacharya, S.P. Bhardwaj, R. Suryanarayanan. Molecular motions in sucrose-PVP and sucrose-sorbitol dispersions-II: implications of annealing on secondary relaxations. Pharm Res, 31(10), 2822-2828 (2014).
- R. Govindarajan, M. Landis, B. Hancock, L.A. Gatlin, R. Suryanarayanan, E.Y. Shalaev. Surface acidity and solid-state compatibility of excipients with an acid-sensitive API: case study of atorvastatin calcium. AAPS PharmSciTech, 16(2), 1-10 (2014).
- S. Bhardwaj, K. Arora, E. Kwong, A. Templeton, S. Clas, R. Suryanarayanan. Mechanism of amorphous itraconazole stabilization in polymer solid dispersions: role of molecular mobility. Mol Pharm, 11(11), 4228-4237 (2014).
- K. Kothari, V. Ragoonanan, R. Suryanarayanan. Influence of molecular mobility on the physical stability of amorphous pharmaceuticals in the supercooled and glassy states. Mol Pharm, 11(9), 3048-3055 (2014).
- P. Sundaramurthi, R. Suryanarayanan. Azithromycin hydrates – implications of processing-induced phase transformations. J Pharm Sci, 103(10), 3095-3106 (2014).
2013
- S. Bhardwaj, R. Suryanarayanan. Molecular mobility as a predictor of the water sorption by annealed amorphous trehalose. Pharm Res, 30(3), 714-720 (2013).
- N. Thakral, V. Ragoonanan, R. Suryanarayanan. Quantification, mechanism, and mitigation of active ingredient phase transformation in tablets. Mol Pharm, 10(8), 3128-3126 (2013).
- K. Arora, S. Thakral, R. Suryanarayanan. Instability in theophylline and carbamazepine hydrate tablets: cocrystal formation due to release of lattice water. Pharm Res, 30(7), 1779-1789 (2013).
- K.E. Dempah, D.H. Barich, A.M. Kaushal, Z. Zong, S.D. Desai, R. Suryanarayanan, L. Kirsch, E.J. Munson. Investigating gabapentin polymorphism using solid-state NMR spectroscopy. PharmSciTech, 14(1), 19-28 (2013).
2011
- S. Bhattacharya, R. Suryanarayanan. Molecular motions in sucrose-PVP and sucrose-sorbitol dispersions: I. Implications of global and local mobility on stability. Pharm Res, 28(9), 2191-2203 (2011).
- A.M. Kaushal, V.R. Vangala, R. Suryanarayanan. Unusual effect of water vapor pressure on dehydration of dibasic calcium phosphate dihydrate. J Pharm Sci, 100(4), 1456-1466 (2011).
- K.K. Arora, N.G. Tayade, R. Suryanarayanan. Unintended water mediated cocrystal formation in carbamazepine and aspirin tablets. Mol Pharm, 8(3), 982-989 (2011). Recipient of 2011 AAPS PPB Outstanding Manuscript Award.
- Z. Zong, S.D. Desai, A.M. Kaushal, D.H. Barich, Hong-Shian Huang, E.J. Munson, R. Suryanarayanan, L.E. Kirsch. The stabilizing effect of moisture on the solid-state degradation of gabapentin. AAPS PharmSciTech, 12(3), 924-931 (2011).
- S. Lohani, Nesmelova, R. Suryanarayanan, D.J.W. Grant. Spectroscopic characterization of molecular aggregates in solutions: Impact on crystallization of indomethacin polymorphs from acetonitrile and ethanol. Cryst Growth Des, 11(6), 2368-2378 (2011).